Major doubt.

Ireland international Sean O’Brien may have played his last game for Leinster ahead of his move to newly-promoted London Irish next season.

The flanker missed Saturday’s PRO14 semi-final win over Munster on Saturday, denying him an RDS farewell as he struggles to overcome a reoccurring hip problem that has once again flared up on him.

Leinster coach Felipe Contepomi says O’Brien is “working hard” to try and make himself available.

“Seán O’Brien, he’s recovering from a hip problem or injury,” Felipe Contepomi confirmed on Monday.

“He’s working hard to be selectable.”

Rob Kearney meanwhile, who could also be set to leave Leinster at the end of the season, should be fit and available for selection this weekend as the eastern province look to defend their crown against a strong Glasgow Warriors side.

“Rob had that return to play. He is training today and should be selectable,” Contepomi added.

Devin Toner meanwhile has already been ruled out with a knee problem.